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Wiki Wiki Summary
Cross product In mathematics, the cross product or vector product (occasionally directed area product, to emphasize its geometric significance) is a binary operation on two vectors in a three-dimensional oriented Euclidean vector space (named here \n \n \n \n E\n \n \n {\displaystyle E}\n ), and is denoted by the symbol \n \n \n \n ×\n \n \n {\displaystyle \times }\n . Given two linearly independent vectors a and b, the cross product, a × b (read "a cross b"), is a vector that is perpendicular to both a and b, and thus normal to the plane containing them.
Back to the Future Back to the Future is a 1985 American science fiction film directed by Robert Zemeckis, and written by Zemeckis and Bob Gale. It stars Michael J. Fox, Christopher Lloyd, Lea Thompson, Crispin Glover, and Thomas F. Wilson.
Sterilization (microbiology) Sterilization refers to any process that removes, kills, or deactivates all forms of life (particularly microorganisms such as fungi, bacteria, spores, and unicellular eukaryotic organisms) and other biological agents such as prions present in or on a specific surface, object, or fluid. Sterilization can be achieved through various means, including heat, chemicals, irradiation, high pressure, and filtration.
Third party (United States) Third party is a term used in the United States for American political parties other than the two dominant parties, currently the Republican and Democratic Parties. Sometimes the phrase "minor party" is used instead of third party.
Dolby Cinema Dolby Cinema is a premium cinema created by Dolby Laboratories that combines Dolby proprietary technologies such as Dolby Vision and Dolby Atmos, as well as other signature entrance and intrinsic design features. The technology competes with IMAX and other premium large formats such as Cinemark's XD and Regal's RPX.\n\n\n== History ==\nThe first installations featuring Dolby Cinema were JT (now Vue) Bioscopen Cinema in Eindhoven, Netherlands on 18 December 2014; followed by Cinesa La Maquinista in Barcelona, Spain.
Economic liberalization Economic liberalization (or economic liberalisation) is the lessening of government regulations and restrictions in an economy in exchange for greater participation by private entities. In politics, the doctrine is associated with classical liberalism and neoliberalism.
Dependant A dependant is a person who relies on another as a primary source of income. A common-law spouse who is financially supported by their partner may also be included in this definition.
List of film production companies This is a list of film production and distribution companies. A production company may specialize in producing their in-house films or own subsidiary development companies.
Aleksandar Rakić Aleksandar Rakić (born February 6, 1992) is an Austrian mixed martial artist. He currently competes in the Light Heavyweight division in the Ultimate Fighting Championship (UFC).
Psychotherapy discontinuation Psychotherapy discontinuation, also known as unilateral termination, patient dropout, and premature termination, is a patient's decision to stop mental health treatment before they have received an adequate number of sessions. In the United States, the prevalence of patient dropout is estimated to be between 40–60% over the course of treatment however, the overwhelming majority of patients will drop after two sessions.
Continuous integration In software engineering, continuous integration (CI) is the practice of merging all developers' working copies to a shared mainline several times a day. Grady Booch first proposed the term CI in his 1991 method, although he did not advocate integrating several times a day.
Library acquisitions Library acquisitions is the department of a library responsible for the selection and purchase of materials or resources. The department may select vendors, negotiate consortium pricing, arrange for standing orders, and select individual titles or resources.Libraries, both physical and digital, usually have four common broad goals that help dictate these responsibilities.
Dexlansoprazole Dexlansoprazole, sold under the trade name Dexilant among others, is a medication which reduces stomach acid. It is used to treat gastroesophageal reflux disease.
Nash equilibrium In game theory, the Nash equilibrium, named after the mathematician John Forbes Nash Jr., is the most common way to define the solution of a non-cooperative game involving two or more players. In a Nash equilibrium, each player is assumed to know the equilibrium strategies of the other players, and no one has anything to gain by changing only one's own strategy.
Line regulation Line regulation is the ability of a power supply to maintain a constant output voltage despite changes to the input voltage, with the output current drawn from the power supply remaining constant.\n\n \n \n \n \n Line Regulation\n \n =\n \n \n \n Δ\n \n V\n \n o\n \n \n \n \n Δ\n \n V\n \n i \n \n \n \n \n \n ⋅\n 100\n %\n \n \n {\displaystyle {\text{Line Regulation}}={\frac {\Delta V_{\text{o}}}{\Delta V_{\text{i }}}}\cdot 100\%}\n where ΔVi is the change in input voltage while ΔVo is the corresponding change in output voltage.
United States Secretary of the Treasury The United States secretary of the treasury is the head of the United States Department of the Treasury, and is the chief financial officer of the federal government of the United States. The secretary of the treasury serves as the principal advisor to the president of the United States on all matters pertaining to economic and fiscal policy.
Symbols of the United States Department of the Treasury Symbols of the United States Department of the Treasury include the Flag of the Treasury Department and the U.S. Treasury Seal. The seal actually predates the department itself, having originated with the Board of Treasury during the period of the Articles of Confederation.
Disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms.
Building regulations in the United Kingdom Building regulations in the United Kingdom are statutory instruments or statutory regulations that seek to ensure that the policies set out in the relevant legislation are carried out. Building regulations approval is required for most building work in the UK. Building regulations that apply across England and Wales are set out in the Building Act 1984 while those that apply across Scotland are set out in the Building (Scotland) Act 2003.
List of sports team names and mascots derived from indigenous peoples The practice of deriving sports team names, imagery, and mascots from Indigenous peoples of North America is a significant phenomenon in the United States and Canada. The popularity of the American Indian in global culture has led to a number of teams in Europe also adopting team names derived from Native Americans.
Attributable fraction among the exposed In epidemiology, attributable fraction among the exposed (AFe) is the proportion of incidents in the exposed group that are attributable to the risk factor. The term attributable risk percent among the exposed is used if the fraction is expressed as a percentage.
North South MRT line The North South line (NSL) is a high-capacity Mass Rapid Transit (MRT) line in Singapore, operated by SMRT Corporation. Coloured red on the rail map, the line is 45 kilometres (28 mi) long and serves 27 stations, 11 of which, between the Bishan and Marina South Pier stations, are underground.
Naturalism (philosophy) In philosophy, naturalism is the idea or belief that only natural laws and forces (as opposed to supernatural ones) operate in the universe.\n\nNaturalism is not so much a special system as a point of view or tendency common to a number of philosophical and religious systems; not so much a well-defined set of positive and negative doctrines as an attitude or spirit pervading and influencing many doctrines.
Industry average Industry averages (of financial ratios) are generally using as benchmarks or tools which helps business to make comparisons that helps to determine its position within the industry and evaluate financial performance of the business. It is a useful tool for business managers and investors, helps with decision making process.
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Population exchange between Poland and Soviet Ukraine The population exchange between Poland and Soviet Ukraine at the end of World War II was based on a treaty signed on 9 September 1944 by the Ukrainian SSR with the newly-formed Polish Committee of National Liberation (PKWN). The exchange stipulated the transfer of ethnic Ukrainians to the Ukrainian SSR and of ethnic Poles and Jews who had Polish citizenship before September 17, 1939 (date of the Soviet Invasion of Poland) to post-war Poland, in accordance with the resolutions of the Yalta and Tehran conferences and the plans about the new Poland–Ukraine border.
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Human rights Human rights are moral principles or norms for certain standards of human behaviour and are regularly protected in municipal and international law. They are commonly understood as inalienable, fundamental rights "to which a person is inherently entitled simply because she or he is a human being" and which are "inherent in all human beings", regardless of their age, ethnic origin, location, language, religion, ethnicity, or any other status.
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Risk Factors
MERIT MEDICAL SYSTEMS INC Item 1A Risk Factors
Our business, operations and financial condition are subject to certain risks and uncertainties
Should one or more of these risks or uncertainties materialize, or should any underlying assumptions prove incorrect, our actual results will vary, and may vary materially from those anticipated, estimated, projected or expected
Among the key factors that may have a direct bearing on our business, operations or financial condition are the factors identified below: Our products may be subject to recall or product liability claims
Our products are used in connection with invasive procedures and in other medical contexts in which it is important that those products function with precision and accuracy
If our products do not function as designed, or are designed improperly, we may choose to or be forced by regulatory agencies to withdraw such products from the market
In addition, if medical personnel or their patients suffer injury as a result of any failure our products to function as designed, or an inappropriate design, we could be subject to lawsuits seeking significant compensatory and punitive damages
Any product recall or lawsuit seeking significant monetary damages may have a material adverse effect on our business, operations or financial condition
14 ______________________________________________________________________ Substantially all of our products are backed by a limited warranty for returns due to defects in quality and workmanship
We maintain a reserve for these future returned products, but the actual costs of such returns may significantly exceed the reserve, which could have a material adverse effect on our financial condition
Termination of relationships with our suppliers, or failure of such suppliers to perform, could disrupt our business
We rely on raw materials, component parts, finished products, and services supplied by outside third parties in connection with our business
For example, substantially all of our products are sterilized by a few entities
In addition, some of our products are manufactured or assembled by third parties
If a supplier of significant raw materials, component parts, finished goods or services were to terminate its relationship with us, or otherwise cease supplying raw materials, component parts, finished goods or services consistent with past practice, our ability to meet our obligations to our end customers may be disrupted
A disruption with respect to numerous products, or with respect to a few significant products, could have a material adverse effect on our business, operations or financial condition
We may be unable to protect our proprietary technology or may infringe on the proprietary technology of others
Our ability to remain competitive is dependent, in part, upon our ability to prevent other companies from using our proprietary technology incorporated into our products
We seek to protect our technology through a combination of patents, trademarks, and trade secrets, as well as licenses, proprietary know-how and confidentiality agreements
We may be unable, however, to prevent others from using our proprietary information, or continue to use such information itself, for numerous reasons, including the following, which could have a material adverse effect on the Company’s business, operations or financial condition: • Our issued patents may not be sufficiently broad to prevent others from copying our proprietary technologies; • Our issued patents may be challenged by third parties and deemed to be overbroad or unenforceable; • Our products may infringe on the patents of others, requiring us to alter or discontinue our manufacture or sale of such products; • Costs associated with seeking enforcement of our patents against infringement, or defending four self against allegations of infringement, may be significant; • Our pending patent applications may not be granted for various reasons, including overbreadth or conflict with an existing patent; and • Other persons may independently develop, or have developed, similar or superior technologies
We may be unable to successfully manage growth, particularly if accomplished through acquisitions
Successful implementation of our business strategy will require that we effectively manage any associated growth
To manage growth effectively, our management will need to continue to implement changes in certain aspects of our business, to improve our information systems and operations to respond to increased demand, to attract and retain qualified personnel and to develop, train and manage an increasing number of management-level and other employees
Growth could place an increasing strain on our management, financial, product design, marketing, distribution and other resources, and we could experience operating difficulties
Any failure to manage growth effectively could have a material adverse effect on our results of operations and financial condition
To the extent that we grow through acquisition, we will face the additional challenges of integrating our current operations, culture, informational management systems and other characteristics with that of the acquired entity
We may incur significant expenses in connection with negotiating and consummating one or more transactions, and we may inherit certain liabilities in connection with the acquisition as a result of our failure or inability to conduct adequate due diligence or otherwise
In addition, we may not realize competitive advantages, synergies or other benefits anticipated in connection with such acquisition(s)
If we do not adequately identify targets for, or manage issues related to its future acquisitions, such acquisitions may have a negative adverse effect on our business and financial results
15 ______________________________________________________________________ A significant adverse change in, or failure to comply with, governing regulations could adversely affect our business
Substantially all of our products are “devices,” as defined in the Federal Food, Drug and Cosmetic Act, (“FDA”) and the manufacture, distribution, record keeping, labeling and advertisement of our products are subject to regulation by the FDA in the United States and its equivalent regulatory agencies in various foreign countries in which our products are manufactured, distributed, labeled, offered and sold
Further, we are subject to continual review and periodic inspections at our current facilities with respect to the FDA’s Quality System Regulations and similar requirements of foreign countries
In addition, we are subject to certain export control restrictions governed by the US Department of the Treasury and may be governed by other regulatory agencies in various foreign countries in which products are exported
Our business, operations or financial condition could be adversely affected if we are found to be out of compliance with governing regulations
If such regulations are amended to become more restrictive and costly to comply with, the costs of compliance could adversely affect our business, operations or financial condition
A significant portion of our revenues are derived from a few products and procedures
A significant portion of our revenues are attributable to sales of our inflation devices
During the year ended December 31, 2005, sales of our inflation devices (including inflation devices sold in custom kits and through OEM channels) accounted for approximately 33prca our total revenues
Any material decline in market demand for our inflation devices could have an adverse effect on our business, operations or financial condition
In addition, the products that have accounted for a majority of our historical revenues are designed for use in connection with a few related medical procedures, including angioplasty, stent placement procedures, and spinal procedures
If subsequent developments in medical technology or drug therapy make such procedures obsolete, or alter the methodology of such procedures so as to eliminate the usefulness of our products, we may experience a material decrease in demand for our products and experience deteriorating financial performance
We may be unable to compete in our markets, particularly if there is a significant change in relevant practices and technology
The market for each of our products is highly competitive
We face competition from many companies, many of which are larger, better established and have greater financial, technical and other resources and greater market presence than we do
Such resources and market presence may enable our competition to more effectively market competing products or to market competing products at reduced prices in order to gain market share
In addition, our ability to compete successfully is dependent, in part, upon our response to changes in technology and to our efforts to develop and market new products which achieve significant market acceptance
Competing companies with substantially greater resources than us are actively engaged in research and development of diagnostic and interventional methods, treatments and procedures that could limit the market for our products and eventually make certain products obsolete
A reduction in the demand for a significant number of our products, or a few key products, could have a material adverse effect on our business, operations or financial condition
The market price of our common stock has been, and may continue to be, volatile
The market price of our common stock has been, and may continue to be, highly volatile for various reasons, including the following, which could have a material adverse effect on the Company’s business, operations or financial condition: • Our announcement of new products or technical innovations, or similar announcements by our competitors; • Development of new procedures that use, or do not use, our technology; • Quarter-to-quarter variances in our financial results; • Claims involving potential infringement of patents and other intellectual property rights; 16 ______________________________________________________________________ • Analysts’ and other projections or recommendations regarding our common stock or medical technology stocks generally; • Any restatement of our financial statements or any investigation of us by the SEC or another regulatory authority; and • A general decline, or rise, of stock prices in the capital markets generally
Fluctuations in Euro and GBP exchange rates may negatively impact our financial results
Fluctuations in the rate of exchange between the Euro and GBP relative to value of the US Dollar could have a negative impact on our margins and financial results
For example, during 2005, the exchange rate between the Euro and the US Dollar resulted in an increase in our gross revenues of approximately dlra263cmam000 and 0dtta09prca in gross profit
For the year ended December 31, 2005, approximately dlra20dtta0 million, or 12dtta0prca, of our sales were denominated in Euros and GBP If the rate of exchange between the Euro and the GBP declines, against the US Dollar, we may not be able to increase the prices we charge our European customers for products whose prices are denominated in Euros and GBP Furthermore, we may be unable or elect not to enter into hedging transactions which could mitigate the effect of declining exchange rates
As a result, as the rate of exchange between Euros and GBP declines, against the US Dollars, our financial results may be negatively impacted
We are dependent upon key personnel
Our success is dependent on key management personnel, including Fred P Lampropoulos, our Chairman of the Board, President and Chief Executive Officer
Lampropoulos is not subject to any agreement prohibiting his departure, and the Company does not maintain key man life insurance on his life
Lampropoulos, or of certain other key management personnel, could materially adversely affect our business and operations
Our success also depends, among other factors, on the successful recruitment and retention of key operations, manufacturing, sales and other personnel
We are subject to work stoppage, transportation and related risks
We manufacture products at various locations in the United States and in Ireland and sell our products worldwide
We depend on third-party transportation companies to deliver supplies necessary to manufacture Merit products from vendors to our various facilities and to move our products to customers, operating divisions and other subsidiaries located worldwide
Our manufacturing operations, and the operations of the transportation companies on which we depend, may be adversely affected by natural disasters or significant human events, such as a war, terrorist attack, riot, strike, slowdown or similar event
Any disruption in our manufacturing or transportation could materially adversely affect our ability to meet customer demands or our operations
Limits on reimbursement imposed by governmental and other programs may adversely affect our business
The cost of a significant portion of medical care is funded by governmental, social security or other insurance programs
Limits on reimbursement imposed by such programs may adversely affect the ability of hospitals and others to purchase our products
In addition, limitations on reimbursement for procedures which utilize our products could adversely affect sales