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Safety integrity level Safety integrity level (SIL) is defined as a relative levels of risk-reduction provided by a safety function, or to specify a target level of risk reduction. In simple terms, SIL is a measurement of performance required for a safety instrumented function (SIF).
Market entry strategy Market entry strategy is a planned distribution and delivery method of goods or services to a new target market. In the import and export of services, it refers to the creation, establishment, and management of contracts in a foreign country.
Systematic risk In finance and economics, systematic risk (in economics often called aggregate risk or undiversifiable risk) is vulnerability to events which affect aggregate outcomes such as broad market returns, total economy-wide resource holdings, or aggregate income. In many contexts, events like earthquakes, epidemics and major weather catastrophes pose aggregate risks that affect not only the distribution but also the total amount of resources.
University of Florida The University of Florida (Florida or UF) is a public land-grant research university in Gainesville, Florida. It is a senior member of the State University System of Florida, traces its origins to 1853, and has operated continuously on its Gainesville campus since September 1906.After the Florida state legislature's creation of performance standards in 2013, the Florida Board of Governors designated the University of Florida as a "preeminent university".
Lahore Resolution The Lahore Resolution (Urdu: قراردادِ لاہور, Qarardad-e-Lahore; Bengali: লাহোর প্রস্তাব, Lahor Prostab), also called Pakistan resolution or declaration of independence of Pakistan, was written and prepared by Muhammad Zafarullah Khan and was presented by A. K. Fazlul Huq, the Prime Minister of Bengal, was a formal political statement adopted by the All-India Muslim League on the occasion of its three-day general session in Lahore on 22–24 March 1940. The resolution called for independent states as seen by the\nstatement:That geographically contiguous units are demarcated regions which should be constituted, with such territorial readjustments as may be necessary that the areas in which the Muslims are numerically in a majority as in the North Western and Eastern Zones of (British) India should be grouped to constitute ‘independent states’ in which the constituent units should be autonomous and sovereign.Although the name "Pakistan" had been proposed by Choudhary Rahmat Ali in his Pakistan Declaration, it was not until after the resolution that it began to be widely used.
DMG Clearances DMG Clearances, Inc is a company based in Hockessin, Delaware, USA, which handles music clearances and licensing for the entertainment industry. DMG Clearances was founded in 1996 by Deborah Mannis-Gardner.The company clears musical compositions for use in films, video games, sampling and Broadway Theater.
Availability heuristic The availability heuristic, also known as availability bias, is a mental shortcut that relies on immediate examples that come to a given person's mind when evaluating a specific topic, concept, method or decision. The availability heuristic operates on the notion that if something can be recalled, it must be important, or at least more important than alternative solutions which are not as readily recalled.
University of Phoenix University of Phoenix (UoPX) is a private for-profit university headquartered in Phoenix, Arizona. Founded in 1976, the university confers certificates and degrees at the certificate, associate, bachelor's, master's, and doctoral degree levels.
Vaccination policy Vaccination policy is a health policy that governments adopt in order to prevent the spread of infectious disease through vaccination. A wide variety of vaccination policies have been developed over the approximately two centuries since the invention of vaccination with the purpose of creating herd immunity, or eradicating a disease altogether, for the population the government aims to protect.
Treacle Treacle () is any uncrystallised syrup made during the refining of sugar. The most common forms of treacle are golden syrup, a pale variety, and a darker variety known as black treacle.
2-Arachidonoylglycerol 2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB1 receptor and the primary endogenous ligand for the CB2 receptor. It is an ester formed from the omega-6 fatty acid arachidonic acid and glycerol.
Lead–acid battery The lead–acid battery is a type of rechargeable battery first invented in 1859 by French physicist Gaston Planté. It is the first type of rechargeable battery ever created.
Customer service Customer service is the provision of service to customers before, during, and after a purchase. This makes it an important part of the value chain of clients.
List of community colleges in the United States with campus housing Most community colleges in the United States do not offer on-campus housing for students. These institutions were established primarily to provide low-cost education for students who commute from their homes.
Implant (medicine) An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. Medical implants are man-made devices, in contrast to a transplant, which is a transplanted biomedical tissue.
DePuy Synthes DePuy Synthes () is a franchise of orthopaedic and neurosurgery companies. Acquired by Johnson & Johnson in 1998, its companies form part of the Johnson & Johnson Medical Devices group.
Teaching Hospital, Peradeniya Teaching Hospital, Peradeniya, is one of the three hospitals in Peradeniya, Sri Lanka. It is one of the leading community teaching hospitals in Sri Lanka, affiliated with the University of Peradeniya.
Wally Uihlein Wally Uihlein (born 1949) in Haverhill, Massachusetts is a retired president and chief executive officer of the Acushnet Company, which comprises the golf brands Titleist, FootJoy, Pinnacle, and Scotty Cameron.\nThe Acushnet Company is publicly traded (NYSE) with a majority share owned by Fila Korea\nUihlein (pronounced "EE-Line") attended the University of Massachusetts Amherst and completed graduate courses in business management at Suffolk University in Boston.
Ignaz Semmelweis Ignaz Philipp Semmelweis (German: [ˈɪɡnaːts ˈzɛml̩vaɪs]; Hungarian: Semmelweis Ignác Fülöp [ˈsɛmmɛlvɛjs ˈiɡnaːts ˈfyløp]; 1 July 1818 – 13 August 1865) was a Hungarian physician and scientist, now known as an early pioneer of antiseptic procedures. Described as the "saviour of mothers", Semmelweis discovered that the incidence of puerperal fever (also known as "childbed fever") could be drastically cut by the use of hand disinfection in obstetrical clinics.
Journal of Cleaner Production The Journal of Cleaner Production is a peer-reviewed academic journal covering transdisciplinary research on cleaner production. It is published by Elsevier.
Future Internet Future Internet is a general term for research activities on new architectures for the Internet.\n\n\n== History ==\nWhile the technical development of the Internet was an extensive research topic from the beginning, an increased public awareness of several critical shortcomings in terms of performance, reliability, scalability, security and many other categories including societal, economical and business aspects, led to future Internet research efforts.
Pelvic thrust The pelvic thrust is the thrusting motion of the pelvic region, which is used for a variety of activities, such as dance or sexual activity.\n\n\n== Sexual activity ==\n\nThe pelvic thrust is used during copulation by many species of mammals, including humans, or for other sexual activities (such as non-penetrative sex).
Patent attorney A patent attorney is an attorney who has the specialized qualifications necessary for representing clients in obtaining patents and acting in all matters and procedures relating to patent law and practice, such as filing patent applications and oppositions to granted patents. The term is used differently in different countries, and thus may or may not require the same legal qualifications as a general legal practitioner.
Rely A relay is an electrically operated switch. It consists of a set of input terminals for a single or multiple control signals, and a set of operating contact terminals.
Directive on the Protection of Trade Secrets The Directive (EU) 2016/943 on the protection of undisclosed know-how and business information (trade secrets) against their unlawful acquisition, use and disclosure is a Directive of the European Parliament and the European Council which was adopted by the European Council on 27 May 2016 following an agreement reached with the European Parliament on 15 December 2015 and amendment by the Parliament on 14 March 2016.The aim of the directive is "to harmonise the existing diverging national laws [within the EU] on the protection against the misappropriation of trade secrets, so that companies can exploit and share their trade secrets with privileged business partners across the Internal Market, turning their innovative ideas into growth and jobs".EU member states are required to "bring into force the laws, regulations and administrative provisions necessary to comply with this Directive" within two years i.e. by May 2018.
The Four Agreements The Four Agreements: A Practical Guide to Personal Freedom is a self-help book by bestselling author Don Miguel Ruiz with Janet Mills. The book offers a code of conduct claiming to be based on ancient Toltec wisdom that advocates freedom from self-limiting beliefs that may cause suffering and limitation in a person's life.
Glossary of patent law terms This is a list of legal terms relating to patents. A patent is not a right to practice or use the invention, but a territorial right to exclude others from commercially exploiting the invention, granted to an inventor or his successor in rights in exchange to a public disclosure of the invention.
Mood disorder A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder where a disturbance in the person's mood is the main underlying feature. The classification is in the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD).
Boston Scientific Boston Scientific Corporation, doing business as Boston Scientific, is a manufacturer of medical devices used in interventional medical specialties, including interventional radiology, interventional cardiology, peripheral interventions, neuromodulation, neurovascular intervention, electrophysiology, cardiac surgery, vascular surgery, endoscopy, oncology, urology and gynecology.\nBoston Scientific is primarily known for the development of the Taxus Stent, a drug-eluting stent which is used to open clogged arteries.
Ecosystem An ecosystem (or ecological system) consists of all the organisms and the physical environment with which they interact.: 458  These biotic and abiotic components are linked together through nutrient cycles and energy flows. Energy enters the system through photosynthesis and is incorporated into plant tissue.
Command center A command center (often called a war room) is any place that is used to provide centralized command for some purpose.\nWhile frequently considered to be a military facility, these can be used in many other cases by governments or businesses.
Forced-air A forced-air central heating system is one which uses air as its heat transfer medium. These systems rely on ductwork, vents, and plenums as means of air distribution, separate from the actual heating and air conditioning systems.
Witzelsucht Witzelsucht (German: [ˈvɪtsl̩ˌzʊxt] "joking addiction") is a set of pure and rare neurological symptoms characterized by a tendency to make puns, or tell inappropriate jokes or pointless stories in socially inappropriate situations. It makes one unable to read sarcasm.
English defamation law Modern libel and slander laws in many countries are originally descended from English defamation law. The history of defamation law in England is somewhat obscure; civil actions for damages seem to have been relatively frequent as far back as the Statute of Gloucester in the reign of Edward I (1272–1307),.
Misrepresentation In common law jurisdictions, a misrepresentation is a false or misleading statement of fact made during negotiations by one party to another, the statement then inducing that other party to enter into a contract. The misled party may normally rescind the contract, and sometimes may be awarded damages as well (or instead of rescission).
Operation Mincemeat Operation Mincemeat was a successful British deception operation of the Second World War to disguise the 1943 Allied invasion of Sicily. Two members of British intelligence obtained the body of Glyndwr Michael, a tramp who died from eating rat poison, dressed him as an officer of the Royal Marines and placed personal items on him identifying him as the fictitious Captain (Acting Major) William Martin.
Financial statement Financial statements (or financial reports) are formal records of the financial activities and position of a business, person, or other entity.\nRelevant financial information is presented in a structured manner and in a form which is easy to understand.
Risk Factors
EXACTECH INC ITEM 1A RISK FACTORS Although it is not possible to predict or identify all risk factors inherent in Exactech’s business, they may include those listed below, which should not be considered an exhaustive statement of all potential risks and uncertainties: • Exactech is subject to extensive government regulation
Failure to obtain government approvals and clearances for new products and/or modifications to existing products on a timely basis would likely have a material adverse effect on the business and financial results of Exactech
A significant recall of one or more of Exactech’s products could have a material adverse effect on Exactech’s business and financial results
Exactech cannot provide assurance that such clearances will be granted or that review by government authority will not involve delays that could materially adversely effect Exactech’s revenues and earnings
• Exactech faces uncertainty relating to the availability of third-party reimbursement for its products
The failure by physicians, hospitals and other users of Exactech’s products to obtain sufficient reimbursement from health care payors for procedures in which Exactech’s products are used or adverse changes in governmental and private payors’ policies toward reimbursement for such procedures could have a material adverse effect on Exactech’s revenues and earnings
• Exactech is required to incur significant expenditures of resources in order to maintain relatively high levels of inventory
As a result of the need to maintain substantial levels of inventory, Exactech is subject to the risk of inventory obsolescence
In the event that a substantial portion of the Company’s inventory becomes obsolete, it could have a material adverse effect on Exactech’s earnings due to the resulting costs associated with the inventory impairment charges
11 ______________________________________________________________________ [36]Table of Contents • Exactech relies upon third party suppliers for its raw materials and supplies
Should the availability and on time delivery of raw materials and supplies needed in the production of its products and services become unreliable or the costs of such increases significantly, it could have a material adverse effect on Exactech’s earnings due to the resulting increased costs of production
• Exactech conducts business in a highly competitive industry
The orthopaedic implant industry is subject to competition in the following areas: product features and design, innovation, service, the ability to maintain new product flow, relationships with key orthopaedic surgeons and hospitals, strength of distribution network, and price
In addition, Exactech faces competition for regional sales representatives within the medical community
Exactech cannot provide assurance that it will be able to compete successfully
• Exactech’s success is partially dependent upon its ability to successfully market new and improved products and the market acceptance of those products
The failure of its products to gain market acceptance would be likely to have a material adverse effect on its revenues and earnings
Exactech cannot provide assurance that new or improved products will gain market acceptance
• Exactech is subject to federal anti-kickback laws and regulations
These laws and regulations prohibit any knowing and willful offer, payment, solicitation or receipt of any form of remuneration, either directly or indirectly, in return for, or to induce: referral of an individual for a service or product for which payment may be made by Medicare, Medicaid or another government sponsored health care program, or purchasing, leasing, ordering or arranging for, or recommending the purchase, lease or order of, any service or product for which payment may be made by a government-sponsored health care program
Those regulators may challenge or review Exactech’s current or future activities under these laws, which would be costly and time consuming, and could increase operating costs, reduce revenues and cash flows
• Exactech holds patents on specific designs and processes and relies on trade secrets and proprietary know-how
Exactech cannot provide assurance as to the breadth or degree of protection which existing or future patents, if any, may afford the Company, that those confidential or proprietary information agreements will not be breached, that the parties from whom Exactech has licensed or otherwise acquired patent rights, proprietary rights and technology have full rights to those patent rights and technology, or that Exactech’s trade secrets and proprietary know-how will not otherwise become known to or independently developed by competitors
• Exactech must devote substantial resources to research and development
Exactech cannot provide assurance that it will be successful in developing competitive new products and/or improving existing products so that its products remain competitive and avoid obsolescence
• Exactech is subject to potential product liability risks, which are inherent in the design, marketing and sale of orthopaedic implants and surgical instrumentation
Exactech cannot provide assurance it will not face claims resulting in substantial liability for which Exactech is not fully insured
A partially or completely uninsured successful claim against Exactech of sufficient magnitude could have a material adverse effect on Exactech’s earnings and cash flows due the cost of defending itself against such a claim
• Exactech is subject to the risk of an inability to secure and maintain adequate levels of product liability insurance coverage on acceptable terms
Product liability insurance premiums are volatile
Should premiums continue to increase significantly, it could have a material adverse effect on Exactech’s earnings and cash flows due to the increase in operating costs that would result
• Exactech’s products, including products that are manufactured by third parties but distributed by us, may be subject to recall or product liability claims
These products are used in medical contexts in which it is important that those products function with precision and accuracy
If these products do not function as designed, or are designed improperly, we or the third party manufacturer of these products may choose to or be forced by regulatory agencies to 12 ______________________________________________________________________ [37]Table of Contents withdraw such products from the market
In addition, if patients suffer injury as a result of any failure of these products to function as designed, or an inappropriate design, we could be subject to lawsuits seeking significant compensatory and punitive damages
Any product recall or lawsuit seeking significant monetary damages may have a material adverse effect on our business, operations or financial condition